Connecting sections of the intestine after the surgical removal of a diseased portion has been the subject of research and invention since the 19th century. The goal has been to find a method to eliminate the leakage associated with anastomosis. Exposing the peritoneal cavity to bowel contaminants can be fatal.
An ideal method would eliminate leaking or constricting and create a wide patent lumen, in an automated quick manner.

Additionally, a method that facilitates a natural healing process, reduces adhesions, leaves no permanent foreign elements behind inside the bowel lumen, and preserves the natural tissue structure would further ensure anastomotic integrity. Stapling falls short of the ideal because it involves puncturing and crushing tissue which can lead to excessive inflammation, infection, and anastomotic leak. Compression anastomosis – pressing bowel ends together until natural healing creates an anastomosis – represents a closer approach to the ideal. However, it has taken many generations to develop a safe and effective implementation: BioDynamix™ Anastomosis - NiTi's proprietary and successful implementation of compression anastomosis based on the unique properties of the shape memory alloy Nitinol.